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COLGELEX™ 3000

Function

Collagen Peptide Hydrolysis Enzyme
High Digestibility • Controlled DH • Targeted Molecular Weight Collagen Peptides

COLGELEX™ 3000 is an advanced collagen peptide production enzyme formulation developed for controlled hydrolysis of collagen and gelatin into high-solubility collagen peptides and collagen hydrolysates. Designed for industrial processors producing collagen ingredients for nutraceuticals, food & beverages, sports nutrition, beauty-from-within, pet nutrition, and functional ingredient markets, COLGELEX™ 3000 helps deliver consistent peptide output with repeatable process control.

The enzyme system is engineered to achieve a target degree of hydrolysis (DH) and a defined molecular weight distribution, enabling manufacturers to standardize product performance, solubility, and processing efficiency across different collagen raw material sources.

Applications:

Benefits

Raw Materials

1) Collagen Peptides with Controlled DH

COLGELEX™ 3000 enables controlled enzymatic hydrolysis so processors can hit a repeatable DH range, supporting standardized product specifications and consistent downstream performance.

2) Targeted Molecular Weight Distribution

Collagen peptide markets demand consistency. COLGELEX™ 3000 is designed to support a defined peptide profile, helping manufacturers produce collagen peptides aligned with target functionality and customer requirements.

3) High Solubility & Process Efficiency

Optimized hydrolysis supports improved solubility and handling for downstream steps like filtration, concentration, spray drying, blending, and formulation.

  • Inconsistent collagen peptide output across batches
  • Poor hydrolysis control causing variable DH and peptide profile
  • Low solubility or difficult dissolution in final collagen peptide products
  • Over-hydrolysis or unstable peptide profiles when using single enzymes
  • Raw material variability affecting collagen hydrolysate performance
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Collagen peptide production requires controlled cleavage of collagen chains into smaller peptide fractions while maintaining process repeatability. COLGELEX™ 3000 uses a synergistic endoprotease + peptidase system to generate peptides with controlled DH and a consistent molecular profile. This allows manufacturers to standardize collagen peptide quality and optimize process economics.

COLGELEX™ 3000 is typically built using a synergistic system of:

  • High-Performance Endoproteases
    Primarily alkaline proteases (serine endopeptidases / subtilisin-type) and/or selected neutral proteases (metalloproteases) to efficiently cleave collagen protein chains into peptide fractions.
  • Exopeptidases / Peptidase Fractions Used to trim peptide ends and optimize the peptide profile, supporting controlled DH, improved solubility, and consistent molecular weight distribution.

COLGELEX™ 1000 – Extraction Aid

For collagen loosening, improved release from skins/bones/frames, and better conversion of by-products into usable collagen/gelatin streams.

COLGELEX™ 2000 – Functional Hydrolysis

For controlled breakdown where functionality and process handling matter—balanced hydrolysis for collagen ingredient performance.

COLGELEX™ 3000 – Collagen Peptide Production

For collagen peptide hydrolysis where consistent DH and molecular weight targeting are key outcomes.

Transforming With
the Science

Food & Agriculture

Protein & Processing

Industrial Applications