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COLGELEX™ 2000

Function

Controlled Hydrolysis • Improved Solubility • Consistent Functional Collagen Ingredients

COLGELEX™ 2000 is a specialized collagen processing enzyme formulation developed for controlled, functional hydrolysis of collagen and gelatin where manufacturers need improved solubility and process handling while maintaining targeted functional performance. The enzyme system is engineered to deliver moderate, controlled breakdown of collagen proteins—ideal for producing functional collagen ingredients used in food processing, nutraceutical intermediates, cosmetics supply chains, and industrial ingredient manufacturing.

COLGELEX™ 2000 is designed to help processors achieve repeatable hydrolysis control, improved batch consistency, and stable ingredient performance across variable collagen raw materials such as fish skins/frames, bovine hides, porcine skins, and collagen-rich trimmings.

Applications:

Benefits

Raw Materials

COLGELEX™ 2000 is typically built using a synergistic combination of:

  • Neutral Proteases (Metalloproteases):
    Controlled protein cleavage under near-neutral conditions, supporting predictable hydrolysis and improved solubility.
  • Alkaline Proteases (Serine Endopeptidases / Subtilisin Family):
    Used in controlled dosage to support efficient hydrolysis where faster reaction kinetics are required.
  • Selected Peptidases (Exopeptidases / Aminopeptidase Fractions – optional by design):
    Used for trimming peptide ends to improve solubility, reduce coarse peptide fractions, and enhance consistency.

1) Controlled Hydrolysis for Functional Collagen

COLGELEX™ 2000 enables moderate hydrolysis where collagen needs to become more soluble and processable while maintaining functional attributes (process dependent).

 2) Improved Solubility & Handling

Hydrolysis improves dispersion and solubility of collagen systems, which can help downstream processing such as filtration, concentration, spray drying, blending, and formulation.

 3) Consistency Across Raw Material Variation

Collagen raw materials vary widely in structure and composition. COLGELEX™ 2000 is designed to deliver repeatable performance and consistent hydrolysis behavior across batches.

  • Poor solubility or difficult dispersion of collagen/gelatin streams
  • Inconsistent hydrolysis leading to variable ingredient performance
  • Over-hydrolysis risk when only high-activity protease is used
  • Batch-to-batch inconsistency due to raw material variability
  • Unstable functional properties in collagen ingredients (process dependent)

COLGELEX™ 2000 uses a controlled blend of endo-acting protease families (and optional peptide-trimming enzymes) to hydrolyze collagen in a predictable manner. By targeting collagen breakdown to a functional range, it supports improved solubility and processing behavior while helping maintain consistent ingredient quality. The system is suitable for plants seeking controlled degree of hydrolysis (DH) and stable molecular profile outputs.

COLGELEX™ 1000 – Extraction Aid

For collagen loosening, improved release from skins/bones/frames, and better conversion of by-products into usable collagen/gelatin streams.

COLGELEX™ 2000 – Functional Hydrolysis

For controlled breakdown where functionality and process handling matter—balanced hydrolysis for collagen ingredient performance.

COLGELEX™ 3000 – Collagen Peptide Production

For collagen peptide hydrolysis where consistent DH and molecular weight targeting are key outcomes.

Transforming With
the Science

Food & Agriculture

Protein & Processing

Industrial Applications